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Rapamycin shows promise in treating cold tumors with specific gene mutation
Rapamycin shows promise in treating cold tumors with specific gene mutation

Immune checkpoint inhibitors (ICIs) emerged in the US about 15 years ago as an exciting class of cancer treatments that have achieved complete and durable remissions for thousands of people with end-stage metastatic cancers. Read more

Medical News - Oct 29
Palvella Therapeutics Announces Scientific Publication in Lymphatic Research and Biology Highlighting Recent Advances in the Pathogenesis of Venous Malformations and the Real-World Use of Rapamycin as an Emerging Targeted Therapy
Palvella Therapeutics Announces Scientific Publication in Lymphatic Research and Biology Highlighting Recent Advances in the Pathogenesis of Venous Malformations and the Real-World Use of Rapamycin as an Emerging Targeted Therapy

Recent advances in understanding venous malformation disease pathogenesis highlight the PI3K/AKT/mTOR pathway as a key driver of disease proliferation, spurring real-world off-label use of systemic rapamycin (sirolimus) Read more

Globenewswire_fr - Sep 17
Palvella Therapeutics Completes Enrollment in Phase 2 TOIVA Trial of QTORINTM Rapamycin for Cutaneous Venous Malformations
Palvella Therapeutics Completes Enrollment in Phase 2 TOIVA Trial of QTORINTM Rapamycin for Cutaneous Venous Malformations

Phase 2 TOIVA trial successfully met recruitment target, enrolling 16 subjects at leading vascular anomaly centers; top-line data expected in mid-December 2025 Read more

Globenewswire_fr - Sep 15